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Propranolol
Propranolol is a non-selective beta-blocker used off-label to treatperformance anxiety by controlling the physical symptoms of stress, such as rapid heartbeat, shaking, sweating, and shortness of breath. Unlike anti-anxiety medications that act on mood or sedation, propranolol works peripherally, blocking the body’s fight-or-flight response—allowing individuals to perform calmly and confidently in high-pressure situations like public speaking, exams, interviews, and performances.
How does it work?
Beta-Adrenergic Blockade
Propranolol blocks β1 and β2 adrenergic receptors, reducing the effects of adrenaline and lowering heart rate, blood pressure, and tremors.
Blunts Physical Symptoms of Anxiety
Prevents symptoms like palpitations, blushing, shaking, and shortness of breath—breaking the feedback loop that amplifies anxiety.
Cognitive Clarity Without Sedation
Because it doesn’t affect mental alertness or cause drowsiness, propranolol is ideal for situational performance anxiety where focus and composure are essential.
Benefits
Non-sedating and non-habit forming
Effective for public speaking, exams, presentations, auditions, and interviews
Can be taken as needed—no daily dosing required
Used by performers, students, executives, and athletes
Long history of safe use in both cardiac and non-cardiac settings
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